产品货号：
Z38240
中文名称：
HSC70/HSPA8抗体
英文名称：
Anti-HSC70/HSPA8 Antibody (Clone#3B6)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-HSC70/HSPA8 Antibody (Clone#3B6) |
| 指标别名 | HSC54;HSC70;HSC71;HSP71;HSP73;HSPA10;HSPA8 |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC/IF,FCM |
| 基因名称 | HSPA8 |
| 克隆号 | 3B6 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG2b |
| 免疫原 | E.coli-derived human Hsc70 recombinant protein (Position:Q520-A614).Human Hsc70 shares 98.9% amino acid (aa) sequence identity with both mouse and rat Hsc70. |
| 实际分子量 | 71KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | protein G purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | HSPA8 (heat shock 70kDa protein 8) also known as HSC70,HSC71,HSP73,HSPA10,FORMERLY,LAP1 or LPS-ASSOCIATED PROTEIN 1,is a heat shock protein that in humans is encoded by the HSPA8 gene.The HSPA8 gene contains 9 exons and spans 5kb.The deduced HSPA8 protein has 646 amino acids and a predicted molecular mass of 70,899 Da.And the HSPA8 gene is mapped on 11q24.1.HSPA8 plays an important role in cells by transiently associating with nascent polypeptides to facilitate correct folding.HSP73 also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell.Rapid decay involves AU-rich binding protein AUF1,which complexes with heat-shock proteins HSC70 and HSP70,translation initiation factor EIF4G,and poly (A)-binding protein.In the absence of Il3,Hsc70 formed a complex with Hsp40 and Hip,and this complex,in association with Eif4g and Pabp,formed a high-stability complex with Bim mRNA that protected it from ribonucleases. |
| Uniprot ID | P11142 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (ZN1928) for Western blot,and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (ZN1866) for IHC(P) and ICC. |
| 基因名全称 | heat shock protein family A (Hsp70) member 8 |
| 蛋白名全称 | Heat shock cognate 71kDa protein |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunocytochemistry in fixed cells 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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